Late thrombotic occlusion of paclitaxel eluting stent more than one year after stent implantation. Lee CH, Tan HC, Ong HY, Teo SG, Lim YT. Heart, 2004, 90(12): 1482.

Impact of reversibility of no-reflow phenomenon on 30-day mortality following percutaneous revascularisation for acute myocardial infarction – insights from a 1328 patient registry. Lee CH, Wong HB, Tan HC, Jun JZ, Teo SG, Ong HY, Low A, Sutandar A, Lim YT. Ann Acad Med Singapore. 2004, 33: S79-81

Impact of reversibility of no reflow phenomenon on 30-day mortality following percutaneous revascularization for acute myocardial infarction-insights from a 1,328 patient registry. Lee CH, Wong HB, Tan HC, Zhang JJ, Teo SG, Ong HY, Low A, Sutandar A, Lim YT. J Interv Cardiol. 2005; 18 (4): 261-6.

Framingham Risk Score inadequately predicts cardiac risk in young patients presenting with a first myocardial infarction. K M G Lee, L C Lee, C W Y Liu, S L Lim, L M Shi, H Y Ong, Y T Lim,  T C Yeo. Ann Acad Med Singapore 2010 Mar;39(3):163-7.

Optimizing the management of elderly colorectal surgery patients. Tan KY, Konishi F, Tan L, Chin WK, Ong HY, Tan P. Surg Today. 2010 Nov;40(11):999-1010.

Apixaban in patients with atrial fibrillation. AVERROES Steering Commitee and Investigators. NEJM. 2011, 364(9): 806

Recalibration of the GRACE score in a Multi-ethnic Asian  Population. Chan MYY Chan MY, Shah BR, Gao F, Sim LL, Chua T, Tan HC, Yeo TC, Ong HY, Foo D, Goh PP, Surrun SK, Pieper KS, Granger CB, Koh TH, Salim A, Tai ES. American Heart Journal. 2011 Am Heart J. 2011. 162(2): 291-9.

Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial. Diener HC, Eikelboom J, Connolly SJ, Joyner CD, Hart RG, Lip GY, O'Donnell M, Hohnloser SH, Hankey GJ, Shestakovska O, Yusuf S; AVERROES Steering Committee and Investigators. Lancet Neurol. 2012 Mar;11(3):225-31.

Growth differentiation factor 15, ST2, high-sensitivity troponin T, and N-terminal pro brain natriuretic peptide in heart failure with preserved vs. reduced ejection fraction. Santhanakrishnan R, Chong JP, Ng TP, Ling LH, Sim D, Leong KT, Yeo PS, Ong HY, Jaufeerally F, Wong R, Chai P, Low AF, Richards AM, Lam CS. Eur J Heart Fail. 2012 Aug 5

Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial.Gheorghiade M, Böhm M, Greene SJ, Fonarow GC, Lewis EF, Zannad F, Solomon SD, Baschiera F, Botha J, Hua TA, Gimpelewicz CR, Jaumont X, Lesogor A, Maggioni AP; ASTRONAUT Investigators and Coordinators. JAMA. 2013 Mar 20;309(11):1125-35.

The Singapore Heart Failure Outcomes and Phenotypes (SHOP) study and Prospective Evaluation of Outcome in Patients with Heart Failure with Preserved Left Ventricular Ejection Fraction (PEOPLE) study: rationale and design. Santhanakrishnan R, Ng TP, Cameron VA, Gamble GD, Ling LH, Sim D, Leong GK, Yeo PS, Ong HY, Jaufeerally F, Wong RC, Chai P, Low AF, Lund M, Devlin G, Troughton R, Richards AM, Doughty RN, Lam CS. J Card Fail. 2013 Mar;19(3):156-62

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial. Maggioni AP, Greene SJ, Fonarow GC, Böhm M, Zannad F, Solomon SD, Lewis EF, Baschiera F, Hua TA, Gimpelewicz CR, Lesogor A, Gheorghiade M; ASTRONAUT Investigators and Coordinators. Eur Heart J. 2013 Oct;34 (40): 3117-27.

Differences in late cardiovascular mortality following acute myocardial infarction in three major Asian ethnic groups. Leonardo Carvalho, Fei Gao, Qifeng Chen, Mikael Hartman, Ling-Ling Sim, Tian-Hai Koh, David Foo, Chee-Tang Chin, Hean-Yee Ong, Khim-Leng Tong, Huay-Cheem Tan, Tiong-Cheng Yeo, Chow-Khuan Yew, Arthur M Richards, Eric D Peterson, Terrance Chua, Mark Y Chan. European Heart Journal: Acute Cardiovascular Care March 5, 2014.

Incidence of venous thromboembolism among patients who underwent major surgery in a public hospital in Singapore. Anindya P. Susanto, Charles Krisnanda, Doreen S-Y. Tan,  Hean-Yee Ong,  Dedy Pratama, Rasjid Soeparwata. Med J Indones 2014, 23,1, 26

Iron deficiency in a multi-ethnic Asian population with and without heart failure: prevalence, clinical correlates, functional significance and prognosis. Yeo TJ, Yeo PS, Ching-Chiew Wong R, Ong HY, Leong KT, Jaufeerally F, Sim D, Santhanakrishnan R, Lim SL, M Y Chan M, Chai P, Low AF, Ling LH, Ng TP, Richards AM, Lam CS. Eur J Heart Fail. 2014 Sep 11. doi: 10.1002/ejhf.161.

Nesiritide fails to reduce the mortality of patients with acute decompensated heart failure: An updated systematic review and cumulative meta-analysis. Yan B, Peng L, Zhao X, Chung H, Li L, Zeng L, Ong H, Wang G. Int J Cardiol. 2014 Aug 23. pii: S0167-5273(14)01623-4.

Angiotensin-neprilysin inhibition versus enalapril in heart failure. McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, Rouleau JL, Shi VC, Solomon SD, Swedberg K, Zile MR; PARADIGM-HF Investigators and Committees. N Engl J Med. 2014 Sep 11;371(11):993-1004

Thickened heart causes a big hole. Tong J, Wong CP, Ong HY, Ling LF. International Journal of Cardiology 2015 Feb 15; 181: 5-7.

Circulating microRNAs in heart failure with reduced and preserved left ventricular ejection fraction. Wong LL, Armugam A, Sepramaniam S, Karolina DS, Lim KY, Lim JY, Chong JP, Ng JY, Chen YT, Chan MM, Chen Z, Yeo PS, Ng TP, Ling LH, Sim D, Leong KT, Ong HY, Jaufeerally F, Wong R, Chai P, Low AF, Lam CS, Jeyaseelan K, Richards AM. 2015 Eur J Heart Fail. 2015 Apr;17(4):393-404.

Long-term prognosis and risk heterogeneity of heart failure complicating acute myocardial infarction. de Carvalho LP, Gao F, Chen Q, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Yeo TC, Chow KY, Richards AM, Peterson ED, Chua T, Chan MY. Am J Cardiol. 2015 Apr 1;115(7):872-8

Impact of the joint association between sex, age and diabetes on long-term mortality after acute myocardial infarction. Gao F, Lam CS, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Machin D, Wong KS, Chan MY, Chua TS. BMC Public Health. 2015 Mar 31;15(1):308.

Circadian Dependence of Infarct Size and Acute Heart Failure in ST Elevation Myocardial Infarction. Seneviratna A, Lim GH, Devi A, Carvalho LP, Chua T, Koh TH, Tan HC, Foo D, Tong KL, Ong HY, Richards AM, Yew CK, Chan MY. PLoS One. 2015 Jun 3; 10(6): e0128526

Comparison of combination therapy of high-dose oral N-acetylcysteine and intravenous sodium bicarbonate hydration with individual therapies in the reduction of Contrast-induced Nephropathy during Cardiac Catheterisation and Percutaneous Coronary Intervention (CONTRAST): A multi-centre, randomised, controlled trial. Chong E, Poh KK, Lu Q, Zhang JJ, Tan N, Hou XM, Ong HY, Azan A, Chen SL, Chen JY, Ali RM, Fang WY, Lau TW, Tan HC. Int J Cardiol. 2015 Dec 15;201:237-42.

Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial. Gheorghiade M, Greene SJ, Butler J, Filippatos G, Lam CS, Maggioni AP, Ponikowski P, Shah SJ, Solomon SD, Kraigher-Krainer E, Samano ET, Müller K, Roessig L, Pieske B; SOCRATES-REDUCED Investigators and Coordinators. JAMA. 2015 Dec 1;314(21):2251-62

Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction. Chan MM, Santhanakrishnan R, Chong JP, Chen Z, Tai BC, Liew OW, Ng TP, Ling LH, Sim D, Leong KT, Yeo PS, Ong HY, Jaufeerally F, Wong RC, Chai P, Low AF, Richards AM, Lam CS. Eur J Heart Fail. 2016 Jan;18 (1):81-8

Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. Santhanakrishnan R, Wang N, Larson MG, Magnani JM, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. J Am Heart Assoc. 2016 Mar 25; 5(3).

Comparison of Long-Term Mortality of Patients Aged ≤40 Versus >40 Years With Acute Myocardial Infarction. Jing M, Gao F, Chen Q, de Carvalho LP, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Yeo TC, Roe MT, Chua T, Chan MY. Am J Cardiol. 2016 May 14

Ethnic differences in the association of QRS duration with ejection fraction and outcome in heart failure. Gijsberts CM, Benson L, Dahlström U, Sim D, Yeo DP, Ong HY, Jaufeerally F, Leong GK, Ling LH, Richards AM, de Kleijn DP, Lund LH, Lam CS. Heart. 2016 Sep 15;102(18):1464-71.

Influence of Ethnicity, Age, and Time on Sex Disparities in Long-Term Cause-Specific Mortality After Acute Myocardial Infarction. Gao F, Lam CS, Yeo KK, Machin D, de Carvalho LP, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Earnest A, Chua T, Chan MY. J Am Heart Assoc. 2016 Oct 6; 5(10)

Prevalence and Clinical Significance of Diabetes in Asian Versus White Patients With Heart Failure. Bank IE, Gijsberts CM, Teng TK, Benson L, Sim D, Yeo PS, Ong HY, Jaufeerally F, Leong GK, Ling LH, Richards AM, de Kleijn DP, Dahlström U, Lund LH, Lam CS. JACC Heart Fail. 2016 Nov 30

Right ventricular dysfunction in left-sided heart failure with preserved versus reduced ejection fraction. Bosch L, Lam CSP, Gong L, Chan SP, Sim D, Yeo D, Jaufeerally F, Leong KTG, Ong HY, Ng TP, Richards AM, Arslan F, Ling LH. Eur J Heart Fail. 2017 Jun 8. doi: 10.1002/ejhf.873.

Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction. Drum CL, Tan WKY, Chan SP, Pakkiri LS, Chong JPC, Liew OW, Ng TP, Ling LH, Sim D, Leong KG, Yeo DPS, Ong HY, Jaufeerally F, Wong RCC, Chai P, Low AF, Davidsson P, Liljeblad M, Söderling AS, Gan LM, Bhat RV, Purnamawati K, Lam CSP, Richards AM. J Am Heart Assoc. 2017 Jun 13;6 (6).

Comparative analysis of recurrent events after presentation with an index myocardial infarction or ischaemic stroke. Yeo KK, Zheng H, Chow KY, Ahmad A, Chan BPL, Chang HM, Chong E, Chua TSJ, Foo DCG, Low LP, Ong MEH, Ong HY, Koh TH, Tan HC, Tang KF, Venketasubramanian N. Eur Heart J Qual Care Clin Outcomes. 2017 Jul 1;3(3):234-242

The prognostic value of highly sensitive cardiac troponin assays for adverse events in men and women with stable heart failure and a preserved vs. reduced ejection fraction. Gohar A, Chong JPC, Liew OW, den Ruijter H, de Kleijn DPV, Sim D, Yeo DPS, Ong HY, Jaufeerally F, Leong GKT, Ling LH, Lam CSP, Richards AM. Eur J Heart Fail. 2017 Aug 28. doi: 10.1002/ejhf.911.

Risk stratification of Asian patients with heart failure and reduced ejection fraction: the effectiveness of the Echo Heart Failure Score. Bosch L, Carluccio E, Coiro S, Gong L, Sim D, Yeo D, Jaufeerally F, Leong KTG, Ong HY, Pin NT, Richards AM, Arslan F, Ling LH, Lam CSP, Ambrosio G. Eur J Heart Fail. 2017 Sep 7. doi: 10.1002/ejhf.922.

Mortality associated with heart failure with preserved vs. reduced ejection fraction in a prospective international multi-ethnic cohort study. Lam CSP, Gamble GD, Ling LH, Sim D, Leong KTG, Yeo PSD, Ong HY, Jaufeerally F, Ng TP, Cameron VA, Poppe K, Lund M, Devlin G, Troughton R, Richards AM, Doughty RN. Eur Heart J. 2018 Jan 29 epublished.

N-terminal pro-B-type natriuretic peptide and prognosis in Caucasian vs. Asian patients with heart failure. Tromp J, Richards AM, Tay WT, Teng TK, Yeo PSD, Sim D, Jaufeerally F, Leong G, Ong HY, Ling LH, van Veldhuisen DJ, Jaarsma T, Voors AA, van der Meer P, de Boer RA, Lam CSP. ESC Heart Fail. 2018 Apr; 5 (2): 279-287.

Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial. Ray KK, Colhoun HM, Szarek M, Baccara-Dinet M, Bhatt DL, Bittner VA, Budaj AJ, Diaz R, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Lopes RD, Moryusef A, Murin J, Pordy R, Ristic AD, Roe MT, Tuñón J, White HD, Zeiher AM, Schwartz GG, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Lancet Diabetes Endocrinol. 2019 Aug;7(8):618-628. doi: 10.1016/S2213-8587(19)30158-5. Epub 2019 Jul 1.

Ethnic differences in atrial fibrillation in patients with heart failure from Asia-Pacific. Tan ESJ, Tay WT, Teng TK, Sim D, Leong KTG, Yeo PSD, Ong HY, Jaufeerally F, Ng TP, Poppe K, Lund M, Devlin G, Troughton RW, Ling LH, Richards AM, Doughty RN, Lam CSP. Heart. 2019 Jun; 105(11): 842-847

Combining Circulating MicroRNA and NT-proBNP to Detect and Categorize Heart Failure Subtypes. Wong LL, Zou R, Zhou L, Lim JY, Phua DCY, Liu C, Chong JPC, Ng JYX, Liew OW, Chan SP, Chen YT, Chan MMY, Yeo PSD, Ng TP, Ling LH, Sim D, Leong KTG, Ong HY, Jaufeerally F, Wong R, Chai P, Low AF, Lund M, Devlin G, Troughton R, Cameron VA, Doughty RN, Lam CSP, Too HP, Richards AM. J Am Coll Cardiol. 2019 Mar 26;73(11):1300-1313

Cognitive impairment in Asian patients with heart failure: prevalence, biomarkers, clinical correlates, and outcomes. Dong Y, Teo SY, Kang K, Tan M, Ling LH, Yeo PSD, Sim D, Jaufeerally F, Leong KTG, Ong HY, Soon D, Lee S, Loh SY, Tan RS, Chan SP, Richards AM, Lam CSP. Eur J Heart Fail. 2019 May;21(5):688-690.

Building a Longitudinal National Integrated Cardiovascular Database―Lessons Learnt From SingCLOUD. Khung Keong Yeo, Hean-Yee Ong, Terrance Chua, Zheng Jie Lim, Jonathan Yap, Hee Hwa Ho, Fazlur Jaufeerally, Khim-Leng Tong, Pipin Kojodjojo, Hwee-Bee Wong, Derrick Heng, Kelvin Bryan Tan, Arthur Mark Richards, Kristine Leok-Kheng Teoh, Kenny Sin, Ngiap Chuan Tan, Simon Biing Ming Lee, Terence Lim, Andy Ta, Edwin Liok, Yee How Lau, Fei Gao, Christian Liman, Joydeep Sarkar, Anders Sahlén, Tian Hai Koh, Mark Y. Chan. Circulation Reports 2020; 2(1) 33-43

Elderly Asian Patients Have Lower Revascularisation Rates and Poorer Outcomes for ST-Elevation Myocardial Infarction Compared to Younger Patients. Cai JX, Yap J, Gao F, Koh TH, Tong KL, Ong HY, Kojodjojo P, Tan HC, Ong ME, Foo D, Ee B, Low LP, Chui P, Yeo KK. Ann Acad Med Singapore. 2020 Jan;49(1): 3-14.

Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T. Aimo A, Januzzi JL Jr, Vergaro G, Richards AM, Lam CSP, Latini R, Anand IS, Cohn JN, Ueland T, Gullestad L, Aukrust P, Brunner-La Rocca HP, Bayes-Genis A, Lupón J, de Boer RA, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K, Gamble GD, Ling LH, Leong KTG, Yeo PSD, Ong HY, Jaufeerally F, Ng TP, Troughton R, Doughty RN, Passino C, Emdin M. Heart failure with preserved ejection fraction diagnostic scores in an Asian population. Ouwerkerk W, Tromp J, Jin X, Jaufeerally F, Yeo PSD, Leong KTG, Ong HY, Ling LH, Loh SY, Sim D, Lee S, Soon D, Chin C, Richards AM, Lam CSP. Eur J Heart Fail. 2020 May 6. doi: 10.1002/ejhf.1851. Online ahead of print.

Regional Variation of Mortality in Heart Failure With Reduced and Preserved Ejection Fraction Across Asia: Outcomes in the ASIAN-HF Registry. MacDonald MR, Tay WT, Teng TK, Anand I, Ling LH, Yap J, Tromp J, Wander GS, Naik A, Ngarmukos T, Siswanto BB, Hung CL, Richards AM, Lam CSP; ASIAN HF investigators. J Am Heart Assoc. 2020 Jan 7;9(1):e012199. doi: 10.1161/JAHA.119.012199. Epub 2019 Dec 19.

CYP2C19 phenotype in South‐East Asian Acute Coronary Syndrome patients and impact on major adverse cardiovascular events. DSY Tan, JWX Aw, M Winther, LL Goh, HY Ong, E Wee, J Liu, HK Ho. J Clin Pharm Ther. 2020 Feb;45(1):52-58

Heart failure with preserved ejection fraction diagnostic scores in an Asian population. Ouwerkerk W, Tromp J, Jin X, Jaufeerally F, Yeo PSD, Leong KTG, Ong HY, Ling LH, Loh SY, Sim D, Lee S, Soon D, Chin C, Richards AM, Lam CSP. Eur J Heart Fail. 2020 May 6.

Atrial Fibrillation and the Prognostic Performance of Biomarkers in Heart Failure. Tan ESJ, Chan SP, Liew OW, Chong JPC, Leong GKT, Yeo DPS, Ong HY, Jaufeerally F, Yap J, Sim D, Ng TP, Ling LH, Lam CSP, Richards AM. Clin Chem. 2021 Jan 8;67(1):216-226 

Relation of Lipoprotein(a) Levels to Incident Type 2 Diabetes and Modification by Alirocumab Treatment. Schwartz GG, Szarek M, Bittner VA, Bhatt DL, Diaz R, Goodman SG, Jukema JW, Loy M, Manvelian G, Pordy R, White HD, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Diabetes Care. 2021 May;44(5):1219-1227.

Socioeconomic Status and Outcomes in Heart Failure With Reduced Ejection Fraction From Asia. Teng TK, Tay WT, Richards AM, Chew TSM, Anand I, Ouwerkerk W, Chandramouli C, Huang W, Lawson CA, Kadam UT, Yap J, Lim S, Hung CL, MacDonald MR, Loh SY, Shimizu W, Tromp J, Lam CSP; ASIAN-HF investigators‡. Circ Cardiovasc Qual Outcomes. 2021 Apr;14(4):e006962.